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Symbol Name ID |
Bptf
bromodomain PHD finger transcription factor MGI:2444008 |
| Darker colors indicate more annotations |
| Human Phenotypes | Microcephaly |
Abnormal cerebral white matter morphology |
Delayed speech and language development |
Intellectual disability |
Global developmental delay |
Motor delay |
| Disease(s) Associated with BPTF | ||||||
| neurodevelopmental disorder with dysmorphic facies and distal limb anomalies |
| Mouse Phenotypes | increased neuron apoptosis |
abnormal neuronal precursor proliferation |
abnormal olfactory sensory neuron morphology |
microgliosis |
decreased brain weight |
decreased forebrain size |
forebrain hypoplasia |
abnormal cerebral cortex morphology |
abnormal stratification in cerebral cortex |
decreased neuronal precursor cell number |
abnormal neuron specification |
decreased prepulse inhibition |
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| Availability | Mouse Genotype | ||||||||||||
| Bptfem1(IMPC)Bay/Bptf+ | |||||||||||||
| Bptftm1.1Cwu/Bptftm1.1Cwu Foxg1tm1(cre)Skm/? (conditional) |
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| Bptftm1.1Cwu/Bptftm1.1Cwu Emx1tm1(cre)Krj/Emx1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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